l Using vaccination to control diseases l
FIGURE 3. CUMULATIVE MORTALITY BEFORE AND AFTER ADDING LIVE E. COLI VACCINE TO A PULLET
PROGRAM.
Review of flock records and structured post mortem surveys will serve as reliable indi-
cators of the success of vaccination and concurrent prevention strategies.
are higher than standard for the age of
the flock through to depletion. Antibiotic therapy only provides short-term
relief and is generally contraindicated.
Vaccination—Two options are avail-
able to protect flocks against APEC.
Killed autogenous vaccines have been
available for several years. These products are expensive and must be injected
once or twice during rearing. Autog-
enous vaccines have been helpful in
reducing mortality in conjunction with
other control measures such as an effective infectious bronchitis vaccination program and adequate ventilation.
A modified live E. coli vaccine has
been available for the past two years.
Two applications by coarse spray are
usually sufficient to significantly lower
or eliminate mortality due to peritonitis. Field data confirms the positive
benefit of protecting flocks using the
live vaccine.
Monitoring—There is currently no
serological test for E. coli. Outbreaks
of peritonitis may easily account for
over half of all flock mortality. Review
of flock records and structured post
mortem surveys will serve as reliable
indicators of the success of vaccination
and concurrent prevention strategies.
Figure 3 shows results achieved in one
complex after implementing a live E.
coli vaccination program. EI
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