Egg Industry - June 2019 - 15

EggIndustry ❙ 15

or serotype. The isolate is sent
to a licensed manufacturer to be
grown to adequate levels, inactivated and mixed with an adjuvant.
Autogenous products are tested
for safety and purity for the initial
serial and an additional identification test is done on subsequent
serials. If isolates are used more
than two years, immunogenicity
testing is also required. 

Issues associated with
the need for vaccine
In the U.S., an infectious coryza
(Avibacterium paragallinarum)
outbreak in commercial layers has
led to shortages of commercial
bacterins and a sharp increase
in demand of autogenous products. The normally tropical disease
has been present for many years
in California, southern Texas and
Florida, but has more recently
emerged in Kentucky, Virginia,
Arizona and Pennsylvania.
Commercial products have a
very long lead time in the production and approval process due to
extended live bird testing in older
pullets of each strain contained in
the product. Vaccination does not
prevent infection, and even wellprotected birds continue to shed
the bacteria, making it very difficult to eradicate without depopulation of the farm.
Bob Evans, technical consultant
at Elanco, says: "All autogenous
products require two doses to
provide full protection. The first
dose stimulates IgM antibodies
and the second dose stimulates
June 2019 ❙ www.WATTAgNet.com

IgG immunity."  He said the
current coryza bacterin shortage
has left some producers with
only enough product to vaccinate
one time, resulting in less-thandesired protection. Clinical signs,

mortality and significant production drops are likely the result of
incomplete immunity.
Several respiratory pathogens
not adequately protected by standard commercial products have


http://www.WATTAgNet.com

Egg Industry - June 2019

Table of Contents for the Digital Edition of Egg Industry - June 2019

Egg Industry - June 2019
To meet cage-free pledges, industry will need to grow 3 times faster
Vaccine options that can improve fl ock health
Probiotic tools may help fl ock health challenges
Egg Industry - June 2019 - CT1
Egg Industry - June 2019 - CT2
Egg Industry - June 2019 - Egg Industry - June 2019
Egg Industry - June 2019 - Cover2
Egg Industry - June 2019 - CT3
Egg Industry - June 2019 - CT4
Egg Industry - June 2019 - 3
Egg Industry - June 2019 - 4
Egg Industry - June 2019 - 5
Egg Industry - June 2019 - To meet cage-free pledges, industry will need to grow 3 times faster
Egg Industry - June 2019 - 7
Egg Industry - June 2019 - 8
Egg Industry - June 2019 - 9
Egg Industry - June 2019 - 10
Egg Industry - June 2019 - 11
Egg Industry - June 2019 - 12
Egg Industry - June 2019 - 13
Egg Industry - June 2019 - Vaccine options that can improve fl ock health
Egg Industry - June 2019 - 15
Egg Industry - June 2019 - 16
Egg Industry - June 2019 - 17
Egg Industry - June 2019 - 18
Egg Industry - June 2019 - Probiotic tools may help fl ock health challenges
Egg Industry - June 2019 - 20
Egg Industry - June 2019 - 21
Egg Industry - June 2019 - 22
Egg Industry - June 2019 - Cover3
Egg Industry - June 2019 - Cover4
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